At 1,100 yards, the .50 BMG is still doing nearly 1,800 fps--and that with a 750-grain bullet. Ouch. Having fired a .50 BMG on 1,000-yard targets, I can tell you it makes a satisfying spray of gravel out of any rock smaller than a steamer trunk. Mild steel plates immediately get holes in them. What is "cover" to lesser cartridges is merely concealment to a .50 BMG.
However, you pay for what you get. The recoil of the .300 is noticeably more than a .308. The .338 is about all most shooters can fire and enjoy the experience. The .50 BMG requires a muzzle brake of some kind simply for the shooter to survive the experience. The larger cartridge size and recoil also require larger launching platforms. On the other hand, a .308 tactical rifle is basically a normal hunting rifle with a heavier barrel and sturdier stock. At 10 to 12 pounds it is like other rifles, and the same-size rifle can be had in .300 Winchester Magnum without too much extra bulk or weight.
A .338 Lapua such as the Sako TRG tips the scales at 11 pounds empty. Add a scope, sling and ammo and it can be as much as 15 pounds. A .50 BMG is almost off the scale. For instance, Barrett's M-82A1 is 31 pounds without scope, ammo, sling or accessories. And you need the weight and muzzle brake to shoot it.
Get as much as you need, but not more than you can carry or handle.
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